Portfolio

Accent Therapeutics is leading the translation of RNA-modifying protein(RMP)biology into promising new precision therapies for cancer.

Expanding the druggable proteome to drug intrinsically disordered proteins.

AM–Pharma is developing disease modifying Alkaline Phosphatase therapeutics.

ApoGen Biotechnologies is developing a new class of therapies that target key drivers of ongoing DNA mutation and tumor evolution.

Aquinnah Pharmaceuticals is developing small molecule therapeutics targeting persistent stress granules for the treatment of neurodegenerative disease.

Artios Pharma is developing cancer treatments that target DNA Damage Response pathways to selectively kill cancer cells.

Capsida Therapeutics is creating a new class of targeted gene therapies for both CNS and non-CNS disorders.

Caraway Therapeutics is developing novel treatments for neurodegenerative disease through modulation of mitophagy and autophagy.

Carisma Therapeutics is developing Chimeric Antigen Receptor-expressing macrophages to target and destroy solid tumors.

DG Medicines is employing a novel drug discovery platform to identify therapeutics for targeted protein degradation.

Disc Medicine is developing therapies addressing ineffective red blood cell production in hematologic diseases.

EndLyz Therapeutics is developing disease-modifying therapeutics which restore endo-lysosomal function and abrogate neurodegeneration in Parkinson’s disease (PD) and other dementias.

Enthera is developing first-in-class therapeutics for severe autoimmune disorders.

E-Scape Bio is developing therapeutics against genetic targets for neurodegenerative disease.

Faze Medicines is pioneering therapeutics based on the groundbreaking new science of biomolecular condensates.

FireCyte is an emerging biotechnology company developing novel treatment strategies focused on the role of microglia and neuroinflammation in progressive neurodegenerative diseases of the eye.

Jnana Therapeutics is building the first drug discovery platform dedicated to the solute carrier family of transporters.

Kojin Therapeutics is developing transformative medicines based on a groundbreaking approach to ferroptosis and cell state biology.

Magnolia Neurosciences is developing potent and highly selective neuroprotective therapies.

Nitrase Therapeutics is developing drugs against a newly identified class of enzymes which play a harmful role in a variety of age and inflammation dependent diseases.

PACT is developing personalized adoptive cell therapies based on neoantigen-targeted T cells against cancer.

Palleon Pharmaceuticals is targeting glycan-sensing checkpoints to unleash both the innate and adaptive immune responses to cancer.

Quanta Therapeutics is pioneering allosteric modulation to control RAS signaling for inhibition of the full scope of RAS-driven cancer types.

Ribometrix is a platform therapeutics company discovering small molecule drugs that target functional 3D RNA structures to treat human disease.

Ribon Therapeutics is discovering first-in-class small molecule inhibitors to block cancer cells' ability to survive under stress.

Stemson Therapeutics is developing a novel treatment for hair loss, using iPS cells to grow new Dermal Papilla and generate hair follicles de novo.

Trishula Therapeutics is dedicated to improving outcomes for people with cancer by developing TTX-030, a first-in-class, anti-CD39 antibody.

IPO, NASDAQ: ALEC

Acquired by Gilead

Acquired by CSL Behring

IPO, NASDAQ: CRBU

Merger with Aduro Biotech, NASDAQ: KDNY

Acquired by Lilly

Acquired by Locust Walk Acquisition Corp (SPAC merger), NASDAQ: EFTR

IPO, NASDAQ: XCUR

IPO, NASDAQ: KALA

Acquired by Zymergen

IPO, NASDAQ: MORF

Acquired by Lilly

Acquired by Amgen

Acquired by Sanofi

Acquired by Gilead