Neuroscience

We are advancing research across several neurodegenerative disorders, including Alzheimer’s disease, multiple sclerosis and Parkinson’s disease.

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Our Foundational Neuroscience Center

On May 18, 2016, we opened a 43,000-square-foot Foundational Neuroscience Center (FNC) in Cambridge, Massachusetts. At the FNC, we will undergo research to gain a deeper understanding of the biological mechanisms underlying neurodegenerative diseases. Our goal is to identify novel therapeutic approaches for bringing relief to our patients living with these chronic, debilitating diseases.

47 million people worldwide living with dementia

1 every 3 seconds new cases of dementia in 2015 worldwide

$818 billion total estimated worldwide cost of dementia in 2015*
*Source: Alzheimer's Disease International

Alzheimer’s Disease

As the number of patients and caregivers seeking help from the health care system increases, Alzheimer’s represents a growing challenge for society. Current treatments simply address the symptoms and do nothing to prevent the progression of the disease or reverse the damage. We are collaborating with the world’s leading Alzheimer’s researchers to identify ways of stopping the disease in its earliest stages. Our anti-tau antibody is being investigated to treat Alzheimer’s disease and progressive supranuclear palsy (PSP) and is advancing to phase 2 development.

Read more about our fight against Alzheimer’s disease

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We’ve discovered that tau may be the true villain in the battle against Alzheimer’s disease, and we’re determined to stop it.

2 million+ people affected by MS worldwide

10 million+ people affected by Parkinson’s disease worldwide

Multiple Sclerosis

Multiple sclerosis, or MS, is a progressive chronic disorder of the nervous system that is most often seen in patients between the ages of 20 and 40. In MS, the immune system attacks a protein called myelin, which forms a protective sheet around neurofibers. When myelin is damaged by MS, neurons struggle to communicate, leading to an accumulation of neuronal loss, atrophy and significant disability over time. We are committed to meeting the needs of patients with MS, and we are currently supporting treatment options that promote nerve protection and facilitate neuronal regeneration.

Parkinson’s Disease

Parkinson’s disease is the second most-common neurodegenerative disorder, affecting more than 10 million people worldwide. In addition to our therapy for advanced Parkinson’s, we are currently exploring other pathways that could provide patients with a new method of treatment for this progressive chronic disease. We are also developing a new delivery system to enhance the patient and caregiver experience while administering our existing therapy for Parkinson’s disease.